Table 1 Significant association of causal genes with rare variants with SBP at T1 and T2 based on chromosome 3 gene-based tests
From: Dynamic pathway analysis of genes associated with blood pressure using whole genome sequence data
Time period and gene | Rare variants | Common variants | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Estimate | SE | zValue | Adjusted pvalue | Estimate | SE | zValue | Adjusted pvalue |
T1 | ABTB1 | 0.71 | 0.24 | 3.01 | 0.0321 | −0.15 | 0.21 | −0.70 | 0.99 |
|  | SCAP | 0.87 | 0.22 | 4.00 | 0.0058 | −0.02 | 0.08 | −0.27 | 0.99 |
|  | PROK2 | 3.30 | 0.90 | 3.66 | 0.011 | −0.19 | 0.21 | −0.93 | 0.99 |
| Â | MUC13 | 0.65 | 0.22 | 2.96 | 0.035 | 0.00 | 0.08 | 0.02 | 1.0 |
T2 | SCAP | 1.06 | 0.27 | 3.89 | 0.0076 | −0.08 | 0.08 | −1.00 | 0.95 |