Figure 1From: Genetic Analysis Workshop 18 single-nucleotide variant prioritization based on protein impact, sequence conservation, and gene annotationVariant prioritization process and summary statistics. Arrows represent the identification progressively of smaller groups of prioritized variants. Variant summary statistics are reported throughout the prioritization process; percentages in round brackets indicate the number of variants retained at each prioritization step. Variant groups expected to produce better association results have a thicker border line. Groups with a significant reduction in variant number are labeled in red.Back to article page