TY - JOUR AU - Wright, C. PY - 2011 DA - 2011// TI - Whole genome sequencing: applications and implications JO - J Med Genet VL - 48 ID - Wright2011 ER - TY - JOUR AU - Panagiotou, O. A. AU - Evangelou, E. AU - Ioannidis, J. P. A. PY - 2010 DA - 2010// TI - Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: a HuGE review JO - Am J Epidemiol VL - 172 UR - https://doi.org/10.1093/aje/kwq234 DO - 10.1093/aje/kwq234 ID - Panagiotou2010 ER - TY - JOUR AU - Madsen, B. E. AU - Browning, S. R. PY - 2009 DA - 2009// TI - A groupwise association test for rare mutations using a weighted sum statistic JO - PLoS Genet VL - 5 UR - https://doi.org/10.1371/journal.pgen.1000384 DO - 10.1371/journal.pgen.1000384 ID - Madsen2009 ER - TY - JOUR AU - Donoho, D. AU - Jin, J. PY - 2004 DA - 2004// TI - Higher criticism for detecting sparse heterogeneous mixtures JO - Ann Stat VL - 32 UR - https://doi.org/10.1214/009053604000000265 DO - 10.1214/009053604000000265 ID - Donoho2004 ER - TY - JOUR AU - Cambien, F. PY - 2011 DA - 2011// TI - Heritability, weak effects, and rare variants in genomewide association studies JO - Clin Chem VL - 57 UR - https://doi.org/10.1373/clinchem.2010.155655 DO - 10.1373/clinchem.2010.155655 ID - Cambien2011 ER - TY - STD TI - Wu Z, Sun Y, He S, Cho J, Zhao H, Jin J: Detection boundary and higher criticism approach for sparse and weak genetic effects. Ann Appl Stat. ID - ref6 ER - TY - CHAP AU - Tukey, J. W. PY - 1976 DA - 1976// TI - T13 N: the higher criticism BT - Course notes, Stat 411 PB - Princeton University CY - Princeton, NJ ID - Tukey1976 ER - TY - JOUR AU - Wu, M. C. AU - Lee, S. AU - Cai, T. AU - Li, Y. AU - Boehnke, M. AU - Lin, X. PY - 2011 DA - 2011// TI - Rare-variant association testing for sequencing data with the sequence kernel association test JO - Am J Hum Genet VL - 89 UR - https://doi.org/10.1016/j.ajhg.2011.05.029 DO - 10.1016/j.ajhg.2011.05.029 ID - Wu2011 ER - TY - CHAP AU - Lee, S. AU - Miropolsky, L. AU - Wu, M. AU - Lee, M. S. S. PY - 2011 DA - 2011// TI - Package "SKAT." BT - CRAN ID - Lee2011 ER - TY - JOUR AU - Hsu, F. AU - Kent, W. J. AU - Clawson, H. AU - Kuhn, R. M. AU - Diekhans, M. AU - Haussler, D. PY - 2006 DA - 2006// TI - The UCSC known genes JO - Bioinformatics VL - 22 UR - https://doi.org/10.1093/bioinformatics/btl048 DO - 10.1093/bioinformatics/btl048 ID - Hsu2006 ER - TY - JOUR AU - Iyengar, S. K. AU - Elston, R. C. PY - 2007 DA - 2007// TI - The genetic basis of complex traits: rare variants or "common gene, common disease"? JO - Methods Mol Biol VL - 376 UR - https://doi.org/10.1007/978-1-59745-389-9_6 DO - 10.1007/978-1-59745-389-9_6 ID - Iyengar2007 ER - TY - JOUR AU - Yang, J. AU - Weedon, M. N. AU - Purcell, S. AU - Lettre, G. AU - Estrada, K. AU - Willer, C. J. AU - Smith, A. V. AU - Ingelsson, E. AU - O'Connell, J. R. AU - Mangino, M. PY - 2011 DA - 2011// TI - Genomic inflation factors under polygenic inheritance JO - Eur J Hum Genet VL - 19 UR - https://doi.org/10.1038/ejhg.2011.39 DO - 10.1038/ejhg.2011.39 ID - Yang2011 ER - TY - JOUR AU - Ionita-Laza, I. AU - Buxbaum, J. D. AU - Laird, N. M. AU - Lange, C. PY - 2011 DA - 2011// TI - A new testing strategy to identify rare variants with either risk or protective effect on disease JO - PLoS Genet VL - 7 UR - https://doi.org/10.1371/journal.pgen.1001289 DO - 10.1371/journal.pgen.1001289 ID - Ionita-Laza2011 ER - TY - JOUR AU - Han, F. AU - Pan, W. PY - 2010 DA - 2010// TI - A data-adaptive sum test for disease association with multiple common or rare variants JO - Hum Hered VL - 70 UR - https://doi.org/10.1159/000288704 DO - 10.1159/000288704 ID - Han2010 ER - TY - JOUR AU - Adzhubei, I. A. AU - Schmidt, S. AU - Peshkin, L. AU - Ramensky, V. E. AU - Gerasimova, A. AU - Bork, P. AU - Kondrashov, A. S. AU - Sunyaev, S. R. PY - 2010 DA - 2010// TI - A method and server for predicting damaging missense mutations JO - Nat Methods VL - 7 UR - https://doi.org/10.1038/nmeth0410-248 DO - 10.1038/nmeth0410-248 ID - Adzhubei2010 ER - TY - JOUR AU - Pollard, K. S. AU - Hubisz, M. J. AU - Rosenbloom, K. R. AU - Siepel, A. PY - 2010 DA - 2010// TI - Detection of nonneutral substitution rates on mammalian phylogenies JO - Genome Res VL - 20 UR - https://doi.org/10.1101/gr.097857.109 DO - 10.1101/gr.097857.109 ID - Pollard2010 ER -