Figure 2

Examination of the association between homozygosity intensities on odd-numbered chromosomes and 3 phenotypes of interest. We used a window size of 5% of single-nucleotide variants (SNVs) on each chromosome. Homozygosity association tests for diastolic blood pressure (DBP) (red line), systolic blood pressure (SBP) (blue line), and hypertension (HTN) status (green line) are shown. Each vertical axis represents the raw p-values (-log₁₀ scale) of the association tests (generalized estimating equation model), and each horizontal axis represents the physical positions (Mb) of anchor SNVs of runs of homozygosity. The arrows point to p-values that were significant after controlling for false discovery rate.