PREST-plus identifies pedigree errors and cryptic relatedness in the GAW18 sample using genome-wide SNP data

BMC Proceedings

Table 1 IBD distribution $p = (p_{0}, p_{1}, p_{2})$ and kinship coefficient $ϕ = p_{1} / 4 + p_{2} / 2$ for the relationship types (reltype) considered by PREST-plus

reltype coding in PREST-plus	Relationship type (abbreviation)	Distribution of IBD sharing			Kinship coefficient, φ
		p ₀	p ₁	p ₂
11	MZ-twin (MZ)	0.000	0.000	1.000	0.50000
10	parent-offspring (PO)	0.000	1.000	0.000	0.25000
1	full-sib (FS)	0.250	0.500	0.250	0.25000
9	half-sib+first cousin (HSFC)	0.375	0.500	0.125	0.18750
2	half-sib (HS)	0.500	0.500	0.000	0.12500
3	grandparent-grandchild (GPC)	0.500	0.500	0.000	0.12500
4	avuncular (AV)	0.500	0.500	0.000	0.12500
5	first cousin (FC)	0.750	0.250	0.000	0.06250
7	half-avuncular (HAV)	0.750	0.250	0.000	0.06250
8	half-first cousin (HFC)	0.875	0.125	0.000	0.03125
6	unrelated (UN)	1.000	0.000	0.000	0.00000
99	other types (Others)	NA	NA	NA	NA

ISSN: 1753-6561