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Table 1 Type I error rate of the GLS-SKAT and FBAT-v1 analysis

From: A generalized least-squares framework for rare-variant analysis in family data

 

Alpha level

 

0.05

0.01

0.001

GLS-SKAT

0.053

9.84 × 10−3

1.07 × 10-3

FBAT-v1

0.051

1.05 × 10−2

1.02 × 10−3

  1. All the genes within 1 Mb of the simulated locus (MAP4) were excluded in this analysis; type I error rate was calculated with test statistics for all 100 simulations.