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Figure 1 | BMC Proceedings

Figure 1

From: Kernel score statistic for dependent data

Figure 1

Simulated SBP associates with gene MAP4. Power estimates of the kernel score statistic with 95% confidence limits over 200 simulated study replicates as function of the significance level. The association between rank-normalized simulated systolic blood pressure and MAP4 was tested, adjusting for age, sex, age × sex interaction, and familial polygenic background. Polymorphic SNP numbers vary between study replicates for very rare SNPs with MAF <1% (range in legend, right panel), but not for MAF 1% to 5% (left panel).

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