Table 1 Power and type I error for population-based methods at α = 0.1%
From: Identifying rare variant associations in population-based and family-based designs
| Â | DBP | SBP | PC1 | |||
|---|---|---|---|---|---|---|
Method | Power | Type I | Power | Type I | Power | Type I |
SKAT-O | 0% | 0.06% | 0% | 0.12% | 0.50% | 0.10% |
SKAT | 0% | 0.05% | 0% | 0.12% | 0.10% | 0.10% |
SUM | 3% | 0.12% | 1.5% | 0.12% | 0% | 0.12% |
rPLS | 13.5% | 0.14% | 20.5% | 0.14% | 14% | 0.13% |