Testing optimally weighted combination of variants for hypertension

BMC Proceedings

Table 1 Top 10 most promising windows associated with DBP

WID	Chr	Physical location	Empirical p_TOW	Empirical p_VW-TOW	Gene	Reference variants
1	3	48117215,48121372	2.34 × 10⁻⁷	0.0005	MAP4
2	3	48063171,48068858	4.95 × 10⁻⁷	0.0005	MAP4
3	3	47957289,47961091	4.09 × 10⁻⁶	0.0006	MAP4	3_47957996 3_47956424 3_47957741
4	3	48034051,48040240	1.42 × 10⁻⁵	0.001	MAP4	3_48040284 3_48040283
5	3	48089115,48094079	2.06 × 10⁻⁵	0.001	MAP4
6	3	48005035,48009105	2.69 × 10⁻⁵	0.0015	MAP4
7	3	47929938,47935009	5.29 × 10⁻⁵	0.001	MAP4
8	3	47912703,47920240	9.06 × 10⁻⁵	0.001	MAP4	3_47913455
9	3	4474736,4477687	0.036	0.071	SUMF1	3_45008742
10	3	56871312,56875674	0.03	0.058	ARHGF3	3_56870810*

Chr, Chromosome; empirical p_TOW , p value of TOW; empirical p_VW-TOW, p value of VW-TOW; reference variants, top 55 variants influencing SBP and DBP in Table 2 of the answers of GAW18; WID, window ID.
*The variants are provided in the Supplemental Table 1 of the answer sheet of GAW18.

ISSN: 1753-6561