Table 2 Nonlinear age effect on genetic association for SBP
a. Age ≤55 years (76 observations) | |||||
|---|---|---|---|---|---|
Rank | SNP no | SNP name | Gene | I-score | Overall I-score |
1 | 14166 | rs9834970 | NA | 77.94 | 20.70 |
2 | 4557 | rs159154 | BRPF1 | 68.90 | 19.03 |
3 | 12457 | rs12493391 | NA | 68.29 | 34.50 |
4 | 58703 | rs2239626 | DGKG | 65.98 | 10.36 |
5 | 269 | rs12715600 | NA | 65.86 | 39.59 |
6 | 32020 | rs1350790 | NA | 65.69 | 12.43 |
7 | 24555 | rs10510935 | NA | 64.50 | 27.97 |
8 | 55694 | rs1454149 | NA | 63.61 | 14.63 |
9 | 24613 | rs4688557 | NA | 61.44 | 11.93 |
10 | 24461 | rs1517931 | NA | 59.60 | 18.07 |
b. Age >55 years (54 observations) | |||||
Rank | SNP no | SNP name | Gene | I-score | Overall I-score |
1 | 49032 | rs9825291 | NA | 172.46 | 63.61 |
2 | 25762 | rs7427984 | NA | 167.36 | 57.98 |
3 | 36285 | rs7647147 | NA | 150.21 | 93.71 |
4 | 60876 | rs2669973 | NA | 149.84 | 59.60 |
5 | 1951 | rs711578 | LRRN1 | 148.09 | 76.97 |
6 | 51800 | rs16851260 | NA | 142.42 | 90.44 |
7 | 49026 | rs9875837 | NA | 139.68 | 55.26 |
8 | 33365 | rs17176829 | NA | 134.32 | 41.67 |
9 | 62781 | rs2686110 | BDH1 | 134.12 | 54.28 |
10 | 60748 | rs1016618 | NA | 133.97 | 74.78 |