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Table 2 Nonlinear age effect on genetic association for SBP

From: Discovering pure gene-environment interactions in blood pressure genome-wide association studies data: a two-step approach incorporating new statistics

a. Age ≤55 years (76 observations)
Rank SNP no SNP name Gene I-score Overall I-score
1 14166 rs9834970 NA 77.94 20.70
2 4557 rs159154 BRPF1 68.90 19.03
3 12457 rs12493391 NA 68.29 34.50
4 58703 rs2239626 DGKG 65.98 10.36
5 269 rs12715600 NA 65.86 39.59
6 32020 rs1350790 NA 65.69 12.43
7 24555 rs10510935 NA 64.50 27.97
8 55694 rs1454149 NA 63.61 14.63
9 24613 rs4688557 NA 61.44 11.93
10 24461 rs1517931 NA 59.60 18.07
b. Age >55 years (54 observations)
Rank SNP no SNP name Gene I-score Overall I-score
1 49032 rs9825291 NA 172.46 63.61
2 25762 rs7427984 NA 167.36 57.98
3 36285 rs7647147 NA 150.21 93.71
4 60876 rs2669973 NA 149.84 59.60
5 1951 rs711578 LRRN1 148.09 76.97
6 51800 rs16851260 NA 142.42 90.44
7 49026 rs9875837 NA 139.68 55.26
8 33365 rs17176829 NA 134.32 41.67
9 62781 rs2686110 BDH1 134.12 54.28
10 60748 rs1016618 NA 133.97 74.78