Table 3 Nonlinear age effect on genetic association for DBP
a. Age ≤55 years (76 observations) | |||||
|---|---|---|---|---|---|
Rank | SNP no | SNP name | Gene | I-score | Overall I-score |
1 | 36509 | rs11706066 | SIDT1 | 50.64 | 23.46 |
2 | 310 | rs12637032 | NA | 50.50 | 23.34 |
3 | 51841 | rs13094783 | NA | 46.00 | 42.74 |
4 | 24461 | rs1517931 | NA | 45.76 | 18.07 |
5 | 26613 | rs7620998 | EIF4E3 | 44.49 | 11.83 |
6 | 14309 | rs336597 | GOLGA4 | 44.42 | 22.46 |
7 | 59571 | rs12696583 | LPP | 44.40 | 9.83 |
8 | 3488 | rs7628504 | GRM7 | 43.66 | 11.35 |
9 | 38122 | rs4687833 | IGSF11 | 43.51 | 13.31 |
10 | 14166 | rs9834970 | NA | 43.22 | 20.70 |
b. Age >55 years (54 observations) | |||||
Rank | SNP no | SNP name | Gene | I-score | OverallI-score |
1 | 51531 | rs1996264 | NA | 66.64 | 40.85 |
2 | 51532 | rs10936243 | NA | 66.64 | 40.85 |
3 | 51534 | rs11918801 | NA | 66.64 | 40.85 |
4 | 51537 | rs12639469 | NA | 66.64 | 40.28 |
5 | 52553 | rs6801576 | NA | 64.79 | 12.85 |
6 | 40969 | rs11717333 | NA | 62.55 | 24.00 |
7 | 51533 | rs10513572 | NA | 62.14 | 17.60 |
8 | 62781 | rs2686110 | BDH1 | 62.14 | 54.28 |
9 | 17446 | rs6799581 | NA | 62.03 | 31.33 |
10 | 40970 | rs13066695 | NA | 59.06 | 16.33 |