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Table 3 Nonlinear age effect on genetic association for DBP

From: Discovering pure gene-environment interactions in blood pressure genome-wide association studies data: a two-step approach incorporating new statistics

a. Age ≤55 years (76 observations)
Rank SNP no SNP name Gene I-score Overall I-score
1 36509 rs11706066 SIDT1 50.64 23.46
2 310 rs12637032 NA 50.50 23.34
3 51841 rs13094783 NA 46.00 42.74
4 24461 rs1517931 NA 45.76 18.07
5 26613 rs7620998 EIF4E3 44.49 11.83
6 14309 rs336597 GOLGA4 44.42 22.46
7 59571 rs12696583 LPP 44.40 9.83
8 3488 rs7628504 GRM7 43.66 11.35
9 38122 rs4687833 IGSF11 43.51 13.31
10 14166 rs9834970 NA 43.22 20.70
b. Age >55 years (54 observations)
Rank SNP no SNP name Gene I-score OverallI-score
1 51531 rs1996264 NA 66.64 40.85
2 51532 rs10936243 NA 66.64 40.85
3 51534 rs11918801 NA 66.64 40.85
4 51537 rs12639469 NA 66.64 40.28
5 52553 rs6801576 NA 64.79 12.85
6 40969 rs11717333 NA 62.55 24.00
7 51533 rs10513572 NA 62.14 17.60
8 62781 rs2686110 BDH1 62.14 54.28
9 17446 rs6799581 NA 62.03 31.33
10 40970 rs13066695 NA 59.06 16.33