Analysis of the progression of systolic blood pressure using imputation of missing phenotype values

BMC Proceedings

Table 1 Imputation of the missing phenotype data

ID	N/C	d(C,N)	AGE ₀	AGE ₁	AGE ₂	AGE ₃	SBP ₀	SBP ₁	SBP ₂	SBP ₃	MED ₀	MED ₁	MED ₂	MED ₃	SMK ₀	SMK ₁	SMK ₂	SMK ₃
T2DG2501049	N		39	45	50	56	110	125	139	149	0	0	0	1	0	0	0	0
T2DG0300150	C	0.072	35	41	45	51	110	121	135	149	0	0	0	1	0	0	0	0
T2DG1700856	C	0.108	33	38	43	50	110	123	130	132	0	0	0	1	0	0	0	0
T2DG0600470	C	0.268	43	46	51	58	133	127	131	185	0	0	0	0	1	1	0	1
...				...				...				...				...
T2DG0300165	C	18.105	50	57	61	66	151	175	176	139	0	0	0	1	0	0	0	0
T2DG0600450	C	21.673	48	53	61	65	136	190	128	130	0	1	1	1	1	0	0	0

The results of imputation are shown for a middle-aged non-completer (N) with ID number T2DG2501049 (see GAW18 real phenotype data) with 2 missing values in each phenotypic variable. The real SBP measurements indicate the possible development of hypertension by this individual. In the table, several values of the distance-function d(C,N) are shown in ascending order. The completer (C) T2DG0300150 is closest to the given non-completer. The imputed values are shown in bold.

ISSN: 1753-6561