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Table 3 Two-marker interaction analysis of ∆SBP/∆t on unrelated individuals

From: Analysis of the progression of systolic blood pressure using imputation of missing phenotype values

SNP1

SNP2

   

rs

Position

Alleles

MAF

HWE

p i

rs

Position

Alleles

MAF

HWE

p i

β ± σ

p i INT

p r INT

rs4686358

3-1028349

T/C

0.15

0.419

0.52

rs17236800

7-37944375

G/A

0.09

0.053

0.19

3.27 ± 0.39

1.20e-13

0.157

rs1321632

3-197092657

T/C

0.06

0.456

0.01

rs7987982

13-110931311

C/T

0.09

0.263

0.22

1.73 ± 0.21

1.24e-13

0.395

rs12632248

3-185139913

A/G

0.10

0.518

0.13

rs10770039

11-9587187

T/C

0.28

0.017

0.56

2.97 ± 0.36

2.78e-13

0.503

rs1482590

3-65219095

T/C

0.20

0.361

0.09

rs10488631

7-128594183

C/T

0.23

0.754

0.22

1.72 ± 0.21

6.82e-13

0.598

rs11716921

3-17175592

G/T

0.17

0.104

0.11

rs6870951

5-133064960

T/C

0.06

0.511

0.43

4.06 ± 0.51

1.45e-12

0.086

rs2220368

5-176140452

A/G

0.21

0.695

0.92

rs7810996

7-73624615

T/C

0.31

0.511

0.78

2.85 ± 0.37

3.48e-12

0.081

rs249209

5-79867209

C/A

0.25

0.069

0.34

rs427488

17-12428237

C/T

0.11

0.163

0.18

2.51 ± 0.32

3.62e-12

0.416

rs7719329

5-108391660

T/C

0.09

0.053

0.13

rs4868699

5-176134402

C/T

0.22

0.222

0.02

2.04 ± 0.27

4.45e-12

0.013

rs524138

5-31465137

A/G

0.07

0.417

0.06

rs4885678

13-80440491

T/G

0.22

0.981

0.50

3.41 ± 0.45

5.90e-12

0.048

rs17242130

5-81154906

C/A

0.06

0.517

0.32

rs2836412

21-39825012

C/T

0.25

0.617

0.08

3.18 ± 0.42

6.38e-12

0.665

rs1677694

5-79936297

T/C

0.17

7.19e-4*

0.23

rs12673145

7-81423463

G/T

0.11

0.679

0.16

2.91 ± 0.38

7.07e-12

0.027

rs3757572

7-45146656

C/A

0.27

0.552

0.55

rs7275197

21-39317417

G/A

0.14

0.235

0.25

3.70 ± 0.49

8.58e-12

0.137

rs1802074

7-37947103

A/G

0.13

0.579

0.50

rs3887013

15-93614127

T/C

0.09

0.240

0.57

3.92 ± 0.52

9.41e-12

0.043

  1. * Indicates p-values for Hardy-Weinberg equilibrium close to the exclusion criterion.
  2. The best results of the 2-marker interaction analysis are shown. Each line contains a pair of SNPs with their IDs; physical base positions; minor/major alleles; Hardy-Weinberg equilibriums (HWEs); p-values p i of the single-marker analysis performed on the imputed phenotypes; regression coefficient β with standard deviation σ of the interaction analysis; p-value p i INT of the interaction analysis performed on the imputed phenotypes; and p-value p r INT of the interaction analysis performed on SNPs listed in the table and on the real phenotypes.
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BMC Proceedings

ISSN: 1753-6561

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