Table 1 TOP 10 hits of SBP on chromosome 3 across the baseline method and the 3 longitudinal methods
From: Comparing baseline and longitudinal measures in association studies
Baseline | Longitudinal | Mean measure | Two-stage | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Effect size | SE | P | Closest* genes | SNP | Effect size | SE | P | Closest* genes | SNP | Effect size | SE | P | Closest* genes | SNP | Effect size | SE | P | Closest* genes |
3_149871159 | 5.31 | 1.22 | 1.63E-05 | LOC646903, | 3_106220130 | −4.36 | 1.02 | 2.16E-05 | LOC100302640 | 3_106220130 | −4.68 | 1.05 | 9.16E-06 | BCHE | 3_165046920 | 2.96 | 0.68 | 1.33E-05 | SLITRK3 |
3_133160911 | 4.02 | 0.93 | 1.83E-05 | BFSP2 | 3_113652027 | 3.77 | 0.89 | 2.34E-05 | GRAMD1C | 3_106220437 | −4.65 | 1.05 | 1.06E-05 | FGF12 | 3_59966975 | 2.52 | 0.58 | 1.59E-05 | FHIT |
3_149894219 | 5.10 | 1.22 | 3.41E-05 | LOC646903, | 3_106217172 | −4.33 | 1.03 | 2.57E-05 | LOC100302640 | 3_106217172 | −4.66 | 1.05 | 1.07E-05 | FGF12 | 3_192240010 | −3.67 | 0.86 | 2.14E-05 | FGF12 |
3_122390279 | 5.24 | 1.26 | 3.65E-05 | PARP14 | 3_165046920 | 4.21 | 1.00 | 2.82E-05 | SLITRK3 | 3_106218053 | −4.62 | 1.07 | 1.64E-05 | FHIT | 3_192239815 | −3.81 | 0.90 | 2.31E-05 | FGF12 |
3_57173021 | 3.87 | 0.93 | 3.75E-05 | IL17RD | 3_106220437 | −4.29 | 1.02 | 2.89E-05 | LOC100302640 | 3_106219390 | −4.62 | 1.07 | 1.64E-05 | DOCK3 | 3_50996289 | 4.18 | 0.99 | 2.55E-05 | DOCK3 |
3_120020489 | 3.73 | 0.90 | 3.95E-05 | LRRC58 | 3_59966975 | 3.58 | 0.86 | 3.15E-05 | FHIT | 3_106231571 | −4.54 | 1.05 | 1.71E-05 | BCHE | 3_165049274 | 2.75 | 0.66 | 3.35E-05 | SLITRK3 |
3_120023242 | 3.73 | 0.90 | 3.95E-05 | LRRC58 | 3_192239815 | −5.47 | 1.31 | 3.20E-05 | FGF12 | 3_106232849 | −4.51 | 1.05 | 1.86E-05 | BCHE | 3_165046402 | 2.71 | 0.66 | 4.21E-05 | SLITRK3 |
3_108188993 | −3.77 | 0.91 | 4.00E-05 | MYH15 | 3_192240010 | −5.28 | 1.27 | 3.27E-05 | FGF12 | 3_106220258 | −4.39 | 1.02 | 1.86E-05 | ZNF385D | 3_165053404 | 2.63 | 0.66 | 6.83E-05 | SLITRK3 |
3_140640076 | 7.59 | 1.84 | 4.08E-05 | SLC25A36 | 3_72678387 | −4.30 | 1.04 | 3.38E-05 | SHQ1 | 3_106220368 | −4.45 | 1.05 | 2.41E-05 | MYH15 | 3_21520730 | 4.60 | 1.16 | 7.82E-05 | ZNF385D |
3_158228266 | −4.87 | 1.18 | 4.31E-05 | RSRC1 | 3_106218053 | −4.28 | 1.04 | 4.20E-05 | LOC100302640 | 3_72678387 | −4.53 | 1.07 | 2.56E-05 | BCHE | 3_113652027 | 2.40 | 0.60 | 7.94E-05 | GRAMD1C |