Table 2 TOP 10 hits of DBP on chromosome 3 across the baseline method and the 3 longitudinal methods
From: Comparing baseline and longitudinal measures in association studies
Baseline | Longitudinal | Mean-measure | Two-stage | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Effect size | SE | P | Closest* genes | SNP | Effect size | SE | P | Closest* genes | SNP | Effect size | SE | P | Closest* genes | SNP | Effect size | SE | P | Closest* genes |
3_164797024 | 4.98 | 1.17 | 2.48E-05 | SI | 3_54748234 | 2.20 | 0.43 | 2.65E-07 | CACNA2D3 | 3_54748234 | 2.23 | 0.44 | 3.73E-07 | CACNA2D3 | 3_54757032 | 1.10 | 0.21 | 1.83E-07 | CACNA2D3 |
3_54748368 | −2.15 | 0.51 | 2.76E-05 | CACNA2D3 | 3_54757032 | 2.21 | 0.43 | 3.21E-07 | CACNA2D3 | 3_54757032 | 2.22 | 0.44 | 5.77E-07 | CACNA2D3 | 3_54748234 | 1.11 | 0.21 | 2.39E-07 | CACNA2D3 |
3_124142019 | 2.85 | 0.69 | 4.62E-05 | KALRN | 3_54748368 | −2.15 | 0.42 | 3.84E-07 | CACNA2D3 | 3_54748368 | -2.17 | 0.43 | 6.80E-07 | CACNA2D3 | 3_54793253 | 1.05 | 0.21 | 6.86E-07 | CACNA2D3 |
3_186144694 | −3.17 | 0.78 | 5.83E-05 | LOC253573 | 3_54784952 | 2.11 | 0.43 | 7.90E-07 | CACNA2D3 | 3_54793253 | 2.09 | 0.43 | 1.67E-06 | CACNA2D3 | 3_54799449 | 1.05 | 0.21 | 7.79E-07 | CACNA2D3 |
3_38845381 | −3.68 | 0.91 | 6.06E-05 | SCN10A | 3_54793253 | 2.08 | 0.42 | 9.59E-07 | CACNA2D3 | 3_54784952 | 2.09 | 0.44 | 2.05E-06 | CACNA2D3 | 3_54784952 | 1.05 | 0.21 | 7.90E-07 | CACNA2D3 |
3_186209848 | −3.05 | 0.78 | 0.000107 | LOC253573 | 3_54779240 | 2.08 | 0.43 | 1.04E-06 | CACNA2D3 | 3_54799449 | 2.09 | 0.44 | 2.31E-06 | CACNA2D3 | 3_54748368 | −1.05 | 0.21 | 8.15E-07 | CACNA2D3 |
3_87619500 | 2.32 | 0.60 | 0.000109 | POU1F1 | 3_54756448 | −2.10 | 0.43 | 1.07E-06 | CACNA2D3 | 3_54756448 | -2.09 | 0.44 | 2.35E-06 | CACNA2D3 | 3_54779240 | 1.03 | 0.21 | 9.61E-07 | CACNA2D3 |
3_177961323 | −2.05 | 0.53 | 0.000115 | KCNMB2-IT1 | 3_54756196 | 2.06 | 0.43 | 1.46E-06 | CACNA2D3 | 3_54756196 | 2.08 | 0.44 | 2.48E-06 | CACNA2D3 | 3_54807320 | 1.03 | 0.21 | 9.67E-07 | CACNA2D3 |
3_72651668 | 2.05 | 0.53 | 0.000132 | SHQ1 | 3_54793450 | −2.07 | 0.43 | 1.57E-06 | CACNA2D3 | 3_54747244 | 2.07 | 0.44 | 2.65E-06 | CACNA2D3 | 3_54756196 | 1.03 | 0.21 | 1.26E-06 | CACNA2D3 |
3_186149493 | −3.04 | 0.79 | 0.000134 | LOC253573 | 3_54740011 | 2.05 | 0.43 | 1.75E-06 | CACNA2D3 | 3_54740011 | 2.07 | 0.44 | 2.67E-06 | CACNA2D3 | 3_54799706 | 1.02 | 0.21 | 1.27E-06 | CACNA2D3 |