Table 1 Power based on analysis of genes at chromosome 3 in simulated datasets.
From: Gene analysis for longitudinal family data using random-effects models
Gene | Number of variants | % Variance of largest functional variant | Power of eb1 | Power of s2 | Power of combined3 |
|---|---|---|---|---|---|
PDCD6I | 466 | 0.00040 | 0.0 | 7.0 | 2.5 |
DNASE1L3 | 115 | 0.00014 | 2.0 | 4.5 | 1.5 |
PTPLB | 493 | 0.00002 | 3.5 | 8.5 | 5.5 |
PAK2 | 409 | 0.00005 | 3.5 | 0.6 | 4.0 |
FBLN2 | 687 | 0.00008 | 0.5 | 3.0 | 0.5 |
FLNB | 956 | 0.00085 | 11.0 | 5.0 | 7.0 |
VPS8 | 1042 | 0.00008 | 3.0 | 12.0 | 5.0 |
RYBP | 347 | 0.00041 | 6.0 | 21.0 | 15.5 |
ZBTB38 | 590 | 0.00031 | 51.0 | 4.0 | 34.5 |
GPR160 2 | 44 | 0.00020 | 3.0 | 19.5 | 12.0 |
SERP1 | 18 | 0.00002 | 0.0 | 5.0 | 1.5 |
SUMF1 | 747 | 0.00010 | 2.0 | 1.0 | 1.0 |
NMNAT3 | 559 | 0.00011 | 5.0 | 5.5 | 6.5 |
ARF4 | 161 | 0.00004 | 1.5 | 3.5 | 2.0 |
MAP4 | 894 | 0.01222 | 99.0 | 30.5 | 97.0 |
MLH1 | 310 | 0.00007 | 2.5 | 2.0 | 1.5 |
ARHGEF3 | 2223 | 0.00007 | 2.0 | 5.0 | 3.0 |
PPP2R3A | 1081 | 0.00025 | 0.5 | 1.0 | 1.0 |
MUC13 | 203 | 0.00007 | 5.0 | 0.5 | 3.0 |
RAD18 | 693 | 0.00003 | 3.0 | 3.5 | 3.5 |
SEMA3F | 134 | 0.00004 | 12.0 | 7.5 | 6.5 |
BTD | 291 | 0.00011 | 1.0 | 2.5 | 1.0 |
ABTB1 | 48 | 0.00053 | 3.5 | 1.1 | 6.5 |
B4GALT4 | 217 | 0.00004 | 2.0 | 4.5 | 3.0 |