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Table 1 p-Values for the top five common single-nucleotide polymorphisms based on the analysis of averaged systolic blood pressure

From: Association analysis of whole genome sequencing data accounting for longitudinal and family designs

     

SBP p-values

   

SNP ID

Gene

Chr

Position

MAF

Baseline

Averaged

Repeated-1

Repeated-2

3_47903424

MAP4

3

47903424

0.124

2.3 × 10-9

6.3 × 10-11

2.2 × 10-9

1.1 × 10-10

3_47903305

MAP4

3

47903305

0.123

3.2 × 10-9

6.5 × 10-11

1.7 × 10-9

1.0 × 10-10

3_47905079

MAP4

3

47905079

0.124

3.2 × 10-9

6.5 × 10-11

1.7 × 10-9

1.0 × 10-10

3_47588649

MAP4

3

47588649

0.122

3.5 × 10-9

6.7 × 10-11

1.8 × 10-9

1.1 × 10-10

3_47990500

MAP4

3

47990500

0.123

3.6 × 10-9

7.2 × 10-11

2.1 × 10-9

1.1 × 10-10

     

DBP p -values

   

SNP ID

Gene

Chr

Position

MAF

Baseline

Averaged

Repeated-1

Repeated-2

3_48064367

MAP4

3

48064367

0.128

1.4 × 10-11

3.6 × 10-13

3.5 × 10-13

3.6 × 10-13

3_47711490

MAP4

3

47711490

0.120

1.8 × 10-11

3.9 × 10-13

5.4 × 10-12

3.9 × 10-13

3_48092335

MAP4

3

48092335

0.127

2.8 × 10-11

4.8 × 10-13

2.2 × 10-12

5.2 × 10-13

3_48105528

MAP4

3

48105528

0.127

2.8 × 10-11

4.8 × 10-13

2.2 × 10-12

5.2 × 10-13

3_47990500

MAP4

3

47990500

0.123

4.9 × 10-11

5.0 × 10-13

5.8 × 10-12

5.4 × 10-13

  1. Note: Repeated-1 and repeated-2 correspond to model (5) and model (4), respectively.
  2. DBP, diastolic blood pressure; MAF, minor allele frequency; SBP, systolic blood pressure