Entropy-based method for assessing the influence of genetic markers and covariates on hypertension: application to Genetic Analysis Workshop 18 data

Table 2 Single-nucleotide polymorphismsin chromosome 3 that are sensitive to the covariates

	No-Attr	Sex		Smoke		Age		Ped		All-Attr
ID	BE	BE	CE	BE	CE	BE	CE	BE	CE	BE
rs6804033	0.669	0.663	0.997	0.659	0.992	0.577	0.979	0.590	0.291	0.341
rs399703	0.669	0.665	0.999	0.659	0.978	0.576	0.997	0.594	0.293	0.338
rs2844347	0.670	0.665	0.999	0.662	0.991	0.577	0.996	0.592	0.295	0.339
rs2555239	0.666	0.662	0.999	0.659	0.999	0.578	0.999	0.595	0.290	0.330
rs1918026	0.663	0.657	0.997	0.654	0.983	0.575	0.996	0.602	0.305	0.349
rs9813198	0.674	0.666	0.988	0.667	0.998	0.577	0.997	0.603	0.292	0.345

Note: BE is the block entropy; CE is the entropy for consistency. These 6 SNPs are among the 156 loci associated with hypertension that were also found by other researchers in the literature.

ISSN: 1753-6561