General analysis workflow. The workflow consists of three parts: input, software and output. The input consists of biological data, which might be protein sequences, structures, RINs as well as additional annotations and biological knowledge retrieved from external sources and databases (shown as gray background for each view). The middle part of the workflow shows the interactions between the different tools and which tool is responsible for the presentation of which data. The output consists of the different views with data mapped onto them and sets of important residues that can be identified through visual exploratory analysis of the available data. The yellow and green boundaries indicate the default selection color used by the different tools.