Figure 2

ProfileGrid visualization of the AKL alignment protein residue distributions. ProfileGrids showing the amino acid usage in the adenylate kinase lid (AKL) domain (A) across all organisms for 1,809 sequences, (B) from Gram negative bacteria for 923 sequences, and (C) from Gram positive bacteria for 886 sequences. The ProfileGrid panels show a representative sequence from the Gram negative (B) and Gram positive (C) alignments while panel (A) shows a majority consensus. For each panel, the color shading is normalized to the number of sequences in each alignment as a color ramp from white (<10%) to dark blue (>= 90% conservation). This figure was exported from the JProfileGrid software and takes advantage of many user defined options such as representing the residue symbols (A) versus the frequency counts (B, C).