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Figure 6 | BMC Proceedings

Figure 6

From: Sequence Bundles: a novel method for visualising, discovering and exploring sequence motifs

Figure 6

Feature 4: Bifurcation of the general consensus sequence in the 'streamgraph' variant of the visualisation. Restructuring the Sequence Bundles chart into a 'streamgraph' visualisation exposes the pattern of variation formed by sequences displaying most frequent residues in positions from 19 to 23 in Gram-positive bacteria (black). Note two interweaving threads bifurcating in position 19 and converging in position 24, one displaying: ...KVEGI... and the other: ...AKADV... Neither of these two parallel threads adhere to the general consensus sequence in Gram-positives which in positions 19-23 is: ...KKAGV... Connection 'bridges' between consensus residues in Gram-positive in positions 19-20, 21-22 and 22-23 are much less significant compared to strongly pronounced interweaving links between other frequent residues. This data feature can be saliently exposed owing to the fact that the Sequence Bundles visualisation method displays sequences as continuous lines and not as discrete items of statistical data in each position (as in the case of the Sequence Logo).

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