Production strategies for the production of red blood cells in stirred tank bioreactors and T-flasks. A. Schematic representation of the expansion strategy. B. Growth profiles and metabolic parameters in bioreactor and manual cultures. C. Characterisation of cellular products resulting from bioreactor and manual cultures. D. Characterisation of haemoglobin content (Hb) in erythrocytes produced ex vivo, after filtration. Part of the figure was used from ''Medical Art Gallery'' (Les Laboratoires Servier).