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Table 1 Summary of top 5 genes associated with SBP, DBP, and HTN

From: Genome-wide joint analysis of single-nucleotide variant sets and gene expression for hypertension and related phenotypes

  Chr BP1 BP2 Gene PG+T PG PT #SNV
SBP 1 27763371 27777626 TMEM222 1.94E-003 1.61E-004 5.87E-001 100
SBP 17 5486374 5490814 MIS12 1.63E-004 2.26E-003 4.46E-003 134
SBP 19 10528205 10581112 PDE4A 3.99E-004 1.30E-001 2.39E-004 311
SBP 3 57376936 57627630 DNAH12 7.87E-003 2.65E-004 9.92E-001 1691
SBP 19 32291486 32313186 MAG 1.74E-003 7.61E-001 3.22E-004 216
DBP 11 72239077 72244176 PHOX2A 1.45E-005 4.17E-001 5.22E-006 112
DBP 19 58182989 58213562 ZNF274 3.68E-004 4.03E-001 1.27E-004 234
DBP 3 10277571 10284767 GHRL 1.52E-004 4.94E-002 1.46E-004 118
DBP 11 43991253 44040694 ALX4 4.16E-004 1.16E-003 2.20E-002 458
DBP 1 61681046 61725423 TM2D1 5.52E-003 5.43E-004 7.86E-001 307
HTN 3 183042973 183066541 TRA2B 1.06E-005 4.91E-003 3.11E-005 496
HTN 7 27445802 27583281 HIBADH 4.05E-004 3.31E-005 7.38E-001 204
HTN 17 4004445 4143020 ZZEF1 3.86E-005 2.24E-002 1.27E-004 871
HTN 3 57277865 57480169 DNAH12 5.23E-003 1.13E-004 9.99E-001 327
HTN 5 131138142 131164051 SLC22A5 2.58E-003 1.34E-004 9.12E-001 151
  1. BP1 first base pair of the gene, BP2 last base pair of the gene, Chr chromosome, P G , P G+T , P T p values from 3 types of tests, and the bolded p value is the smallest of the 3 p values, #SNV number of single nucleotide variants in the gene region
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BMC Proceedings

ISSN: 1753-6561

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