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Table 1 Empirical sizes calculated with 7210 genes from 200 replicates

From: Comparing family-based rare variant association tests for dichotomous phenotypes

α RV-TDT GEE-KM PedCMC PedGene FARVAT
CMC/BRVVT-BRV/VT-CMC/WSS Kernel/burden C-alpha/burden/SKAT-O
0.1 0.0108/0.0130/0/0/0 0.2137 0.0714 0.0895/0.0879 0.0865/0.0888/0.0864
0.05 0.0040/0.0040/0/0/0 0.1050 0.0357 0.0490/0.0433 0.0445/0.0434/0.0450
0.01 0.0009/0.0009/0/0/0 0.0163 0.0079 0.0141/0.0098 0.0112/0.0092/0.0115
0.005 0.0004/0.0004/0/0/0 0.0066 0.0043 0.0086/0.0056 0.0065/0.0050/0.0068
0.001 0/0/0/0/0 0.0006 0.0011 0.0029/0.0017 0.0020/0.0013/0.0021