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Table 1 Top 10 signals from gene-based SKAT

From: Comparison of multiple single-nucleotide variant association tests in a meta-analysis of Genetic Analysis Workshop 19 family and unrelated data

Gene

Chromosome

Position

# SNVs

SKAT p value

Haplotype p value

ALCAM

3

105243142

28

7.00E-05

0.0095

LMTK2

7

97784102

84

0.000162

0.028

ZBTB4

17

7365289

58

0.000138

0.0036

UBQLNL

11

5536309

30

0.000214

4.1E-05

WDR16

17

9480017

30

0.000269

0.019

KCNN4

19

44273159

22

0.000281

–

SLC19A1

21

46934932

85

0.000386

0.025

TRPM5

11

2426196

159

0.00042

0.19

PRRX2

9

132481557

12

0.000434

1.0E-04

NNT

5

43609313

35

0.000618

0.031

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BMC Proceedings

ISSN: 1753-6561

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