Table 2 Top 10 signals for gene-based haplotype analysis
Gene | Chromosome | Position | # SNVs | # Haplotype | Haplotype p value | SKAT p value |
|---|---|---|---|---|---|---|
ADSS | 1 | 244572897 | 3 | 3 | 5.9E-08 | 0.43 |
FPGT | 1 | 74670081 | 5 | 5 | 6.7E-08 | 1.4E-03 |
MYL10 | 7 | 101256771 | 4 | 6 | 1.7E-07 | 2.1E-03 |
FGR | 1 | 27939439 | 2 | 3 | 1.8E-07 | 0.12 |
KIF2A | 5 | 61642994 | 5 | 3 | 2.0E-07 | 0.91 |
SPARC | 5 | 151043147 | 3 | 4 | 3.3E-07 | 8.5E-02 |
CYP2A13 | 19 | 41594384 | 8 | 6 | 3.4E-07 | 0.32 |
PKLR | 1 | 155260382 | 3 | 4 | 3.7E-07 | 1.2E-03 |
CADM4 | 19 | 44127515 | 2 | 3 | 4.2E-07 | 4.7E-02 |
ZNF529 | 19 | 37037771 | 7 | 7 | 5.7E-07 | 0.22 |