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Table 2 Genetic variance and power (DBP)

From: Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals

 

# SNPs

# Fn. SNPsa

% Var. Explaineda

% Var. of Largest Fn. Varianta

MONSTER

FBAT

RV

LC

Min P

MAP4

919

15

6.48

2.29

1.00

0.57

0.82

0.37

TNN

493

18

4.08

1.98

0.31

0.12

0.31

0.13

LEPR

899

8

2.50

2.19

0.03

0.05

0.16

0.08

Average

770.3

13.7

4.35

1.78

0.44

0.24

0.43

0.19

Computation time (min)

39

13

21

52

  1. Fn functional, Var variance
  2. Power is calculated using a type I error of 0.05
  3. aData on the number of SNPs simulated to be functional and the percent of variance explained by these functional SNPs has been provided by Almasy et al. [23]