Table 1 Type I error rates and 95 % confidence intervals for the CAPL-burden and CAPL-SKAT at α = 0.05
From: A combined association test for rare variants using family and case-control data
Population | Number of variants | CAPL-burden | CAPL-SKAT |
|---|---|---|---|
CEU | 50 | 0.056 (0.049, 0.062) | 0.047 (0.041, 0.052) |
CEU | 100 | 0.049 (0.043, 0.054) | 0.042 (0.036, 0.047) |
MXL | 50 | 0.050 (0.043, 0.056) | 0.045 (0.039, 0.050) |
MXL | 100 | 0.049 (0.043, 0.054) | 0.054 (0.047, 0.060) |
CEU + MXL | 100 | 0.045 (0.039, 0.051) | 0.043 (0.037, 0.048) |