Table 1 Descriptive characteristics of base population, potential cases and controls, and selected cases and controls
From: Prioritization of family member sequencing for the detection of rare variants
|  | Base cases (n = 261) | Base controls (n = 458) | Potential cases (n = 170) | Potential controls (n = 277) | Selected cases (n = 128) | Selected controls (n = 188) | Selected cases vs. controls |
|---|---|---|---|---|---|---|---|
Genes excluded | 42 | 39 | 38 | NA | |||
Gene sets | 1389 | 1377 | 1345 | NA | |||
Age (years) | 52.4 (17.3) | 33.0 (13.6) | 49.5 (17.0) | 35.2 (14.8) | 49.1 (17.4) | 35.8 (14.9) | <0.0001 |
16.1–99.0 | 11.1–83.0 | 16.1–90.3 | 12.1–83.0 | 16.1–85.0 | 16.0–83.0 | ||
SBP (mm Hg) | 143 (9.5) | 116 (13.0) | 146 (8.7) | 109 (11.7) | 146 (8.7) | 110 (11.4) | <0.0001 |
102–186 | 72–140 | 123–186 | 72–139 | 123–186 | 72–139 | ||
DBP (mm Hg) | 78 (9.9) | 70 (8.7) | 80 (9.3) | 68 (8.5) | 80 (9.3) | 69 (8.1) | <0.0001 |
49–102 | 46–89 | 54–102 | 46–87 | 54–102 | 48–87 | ||
Males | 117 (45) | 194 (42) | 70 (41) | 112 (40) | 56 (44) | 75 (40) | NS |
Smokers | 54 (21) | 97 (21) | 35 (21) | 59 (21) | 30 (23) | 46 (25) | NS |