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Table 2 Multivariate QTL analysis of the real, 8-variate trait (SBP i , DBP i i = 1, 2, 3, 4) from the family data with 849 individuals and 3.1 million SNPs (after filtering). Estimated mean effects under the null model (no SNPs included) using the theoretical kinship matrix for the additive polygenic variance component

From: Genome-wide QTL and eQTL analyses using Mendel

Mean effects

SBP si

DBPs i

β Sex

10.21

4.24

\( {\beta}_{{\mathrm{Age}}_i} \)

0.32

0.02

\( {\beta}_{{\mathrm{BPmed}}_i} \)

3.11

10.07

\( {\beta}_{{\mathrm{Smoke}}_i} \)

1.53

1.84

\( {\beta}_{{\mathrm{Sex}}_i\times {\mathrm{BPmed}}_i} \)

−3.20

−1.84

\( {\beta}_{{\mathrm{Sex}}_i\times {\mathrm{Smoke}}_i} \)

0.30

−0.73

\( {\beta}_{{\mathrm{Sex}}_i\times {\mathrm{Age}}_i} \)

0.41

0.14

\( {\beta}_{{\mathrm{BPmed}}_i\times {\mathrm{Smoke}}_i} \)

3.83

2.43

\( {\beta}_{{\mathrm{BPmed}}_i\times {\mathrm{Age}}_i} \)

0.01

−0.35

\( {\beta}_{{\mathrm{Smoke}}_i\times {\mathrm{Age}}_i} \)

−0.06

−0.06