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Table 1 Top 20 genes with adjusted p value of <0.05 from the Seq-aSum-VS test for either SNP or DBP

From: Powerful association test combining rare variant and gene expression using family data from Genetic Analysis Workshop 19

  Gene Chr # RVs p Value s W s p * s p Value D W D p * D
1 NAIF1 9 23 <0.002 1.306 <0.002 0.002 0.825 0.002
2 SPATA13-AS1 13 7 <0.002 0.986 <0.003 0.018 0.835 0.022
3 UTP11L 1 34 <0.002 0.828 <0.003 0.006 1.168 0.005
4 C1orf174 1 36 <0.002 2.473 <0.002 <0.002 2.049 <0.002
5 KRTAP23-1 21 2 <0.002 0.955 <0.003 <0.002 0.586 <0.004
6 ZNF14 19 49 <0.002 0.625 <0.004 0.012 0.788 0.015
7 LOC101926911 15 28 <0.002 0.526 <0.004 0.008 0.856 0.009
8 SGSH 17 45 0.002 1.839 0.001 0.004 0.842 0.005
9 UROD 1 6 0.002 1.523 0.001 0.040 1.870 0.021
10 HES2 1 13 0.002 0.858 0.002 0.016 0.694 0.023
11 CHRNB1 17 50 0.008 2.413 0.003 0.022 1.422 0.015
12 ZBTB47 3 42 0.004 1.106 0.004 0.076 1.465 0.052
13 MIR4467 7 2 0.004 0.879 0.005 0.006 0.848 0.007
14 GTF3A 13 31 0.006 0.918 0.007 0.002 1.178 0.002
15 HMGB4 1 20 0.012 1.593 0.008 0.062 1.248 0.050
16 TEKT2 1 27 0.012 1.481 0.008 0.006 1.782 0.003
17 COX8A 11 12 0.006 0.722 0.008 0.006 1.043 0.006
18 MED29 19 27 0.010 1.202 0.008 0.026 0.637 0.041
19 C11orf21 11 32 0.008 0.951 0.008 0.038 1.172 0.032
20 PRAMEF17 1 5 0.014 1.656 0.008 0.054 0.721 0.075
  1. Chr chromosome, p * s weight adjusted p value for SBP, p value s p value for SBP, # RVs number of rare variants identified in the gene, W s weight for SBP
  2. Subscript D represents statistics for DBP