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Fig. 1 | BMC Proceedings

Fig. 1

From: Comparing strategies for combined testing of rare and common variants in whole sequence and genome-wide genotype data

Fig. 1

Test power on simulated SBP may greatly depend on SNP weights. Left and middle panels: Power of the kernel score test over 200 study replicates of simulated SBP as function of the significance level for different SNP weights and SNP panels. Right panel: Power of joint tests of rare and common SNPs at 2 significance levels α = 0.05, 10−6 when using 1/ν-weights on the sequence of gene-containing LD-blocks. Power estimates for LEPR (positions 65743083 to 66106465) and FLT3 (28490385–28713642) (not shown) were highly similar to TNN

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BMC Proceedings

ISSN: 1753-6561

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