Table 1 P Values of the top genes based on analyzing real data
From: Incorporation of protein binding effects into likelihood ratio test for exome sequencing data
Genes | Chr | C-alpha (4 genes) | CMC (3 genes) | LRT (5 genes) | LRT-DIR (7 genes) | LRT-BS (8 genes) |
|---|---|---|---|---|---|---|
C7orf55-LUC7L2 | 7 | 1.99E-04 (1) | 9.80E-03 (115) | 2.79E-01 (3005) | 2.41E-01 (2659) | 2.13E-01 (2385) |
LUC7L2 | 7 | 1.99E-04 (1) | 9.80E-03 (115) | 2.57E-01 (2773) | 2.85E-01 (3119) | 2.25E-01 (2496) |
DNAH9 | 17 | 1.99E-04 (1) | 4.11E-02 (495) | 8.81E-01 (8461) | 9.25E-01 (8834) | 7.53E-01 (7822) |
AKAP8 | 19 | 1.99E-04 (1) | 4.21E-02 (504) | 2.43E-01 (2636) | 2.29E-01 (2534) | 2.75E-01 (3021) |
MSL2 | 3 | 3.80E-3 (68) | 4.39E-05 (1) | 2.00E-01 (2) | ≤1.00E-4 (1) | ≤1.00E-4 (1) |
ZBTB4 | 17 | 8.00E-4 (12) | 9.21E-05 (2) | 1.83E-02 (246) | 4.11E-02 (525) | 2.35E-01 (2479) |
BCHE | 3 | 1.86E-2 (287) | 1.55E-04 (3) | 9.11E-2 (1117) | 8.53E-2 (1070) | 8.69E-2 (1073) |
LZIC | 1 | 7.20E-3 (112) | 1.00E-2 (121) | ≤1.00E-4 (1) | ≤1.00E-4 (1) | ≤1.00E-4 (1) |
ABO | 9 | 4.08E-1 (4715) | 1.92E-2 (2112) | 6.00E-4 (4) | ≤1.00E-4 (1) | 4.00E-4 (3) |
COL15A1 | 9 | 7.36E-1 (7836) | 1.56E-1 (2030) | ≤1.00E-4 (1) | ≤1.00E-4 (1) | ≤1.00E-4 (1) |
PSPC1 | 13 | 3.06E-1 (3366) | 6.73E-1 (7481) | 2.00E-4 (2) | ≤1.00E-4 (1) | ≤1.00E-4 (1) |
TLN2 | 15 | 3.70E-1 (4036) | 3.63E-1 (4173) | 2.00E-4 (2) | ≤1.00E-4 (1) | ≤1.00E-4 (1) |
ZNF557 | 19 | 6.45E-1 (6876) | 2.38E-1 (2870) | 4.00E-4 (3) | ≤1.00E-4 (1) | ≤1.00E-4 (1) |
ITGA2 | 5 | 6.69E-1 (7123) | 5.08E-1 (5776) | ≤1.00E-4 (1) | 2.00E-4 (2) | 4.00E-4 (3) |
ZMYM5 | 13 | 8.51E-1 (8932) | 7.67E-1 (9624) | 2.00E-4 (2) | 2.00E-4 (2) | ≤1.00E-4 (1) |
YIPF2 | 19 | 4.18E-1 (4538) | 6.24E-2 (1007) | ≤1.00E-4 (1) | 2.00E-4 (2) | ≤1.00E-4 (1) |
PAEP | 9 | 4.52E-1 (4862) | 4.92E-1 (5617) | ≤1.00E-4 (1) | 2.00E-3 (31) | 6.00E-4 (4) |