Table 2 Results of the SNVs with the smallest p values in the association tests of H 0 : β 1 = 0 for GE under the copula and univariate models
From: Genetic association analysis based on a joint model of gene expression and blood pressure
SNV | MAF | Location | Copula | Univariate | ||||
|---|---|---|---|---|---|---|---|---|
\( \hat{\beta_1} \) (SE) | p value | Adj. p value | \( \hat{\beta_1} \) (SE) | p value | Adj. p value | |||
rs2314667 | 0.32 | UBA52 (upstream) | 0.88 (5.42 × 10− 02) | 6.47 × 10− 60 | 1.71 × 10− 55 | 0.88 (5.49 × 10− 02) | 3.21 × 10− 26 | 8.71 × 10− 22 |
rs2314664 | 0.33 | UBA52 (downstream) | 0.85 (5.52 × 10− 02) | 5.01 × 10− 54 | 7.97 × 10− 50 | 0.85 (5.59 × 10− 02) | 7.24 × 10− 25 | 1.18 × 10− 20 |
rs2314666 | 0.34 | UBA52 (downstream) | 0.85 (5.66 × 10− 02) | 2.88 × 10− 51 | 3.81 × 10− 47 | 0.85 (5.73 × 10− 02) | 3.41 × 10− 24 | 4.62 × 10− 20 |