Skip to main content

Table 2 List of genes with top pathway-based signals for real and simulated phenotypes

From: Association of polymorphisms in the aldosterone-regulated sodium reabsorption pathway with blood pressure among Hispanics

Phenotype Gene (variant) p Value
Unadjusted Bonferroni adjusted
Real phenotypes
DBP PRKCA (rs1010546) 0.0014 0.0291
SBP PRKCA (rs1010546) 0.0015 0.0316
MAP PRKCA (rs1010546 0.0006 0.0117
PP INSR (rs3815902) 0.0130 0.2730
Hypertension PRKCA (rs1010546) 0.0029 0.0624
Simulated phenotypes
DBP PRKCA (rs2227857) 0.0025 0.0528
SBP PRKCA (rs2227857) 0.0009 0.0205
MAP PRKCA (rs2227857) 0.0004 0.0080
PP INSR (rs2860177) 0.0359 0.7549
Hypertension ATP1A4 (rs11265338) 0.0045 0.0953