Fig. 2From: Comparison of 2 models for gene–environment interactions: an example of simulated gene–medication interactions on systolic blood pressure in family-based dataComparison of the false-positive proportions (FPPs) and 95 % confidence intervals for the interaction model (solid line) and med-diff approaches (dashed line) and 200 replicates of true negative findings on the odd-numbered chromosomes using the 1DF (gray) and 2DF tests (black) across bins of minor allele frequency (>0.1 to 50 %). Note: False-positive proportions were calculated after excluding SNPs at the CYP3A43 locus (chr7:98957518 to 99957518)Back to article page