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Fig. 2 | BMC Proceedings

Fig. 2

From: Type I error rates of rare single nucleotide variants are inflated in tests of association with non–normally distributed traits using simple linear regression methods

Fig. 2

Distribution of type I error rate by MAF. Type I error rate versus MAF. Different color/symbols indicate different null traits. Each point indicates average type I error rate at the critical level of 10-5 of SNVs grouped by MAF; extremely rare variants (MAF < 0.0025) are classified by number of occurrences of the rare allele, while rare (0.0025 ≤ MAF < 0.05) and common (MAF ≥ 0.05) ones are classified by MAF range

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BMC Proceedings

ISSN: 1753-6561

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