Table 2 Background polygenic SNPs. All markers are simulated with the same heritability (hg2 = 0.001) affecting triglycerides at visits 3 and 4
markname | chrom | position | Gene | role | strand_affy | allele_affy | coded_all | noncoded_all | coded_af | P_HWE | Callrate | SNPID |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs12037545 | 1 | 14875400 | KIAA1026 | intron | – | A/G | G | A | 0.51764 | 0.378 | 1 | SNP_A_2245928 |
rs11102122 | 1 | 1.11E + 08 | + | G/T | T | G | 0.534672 | 0.5963 | 0.997625 | SNP_A_8451677 | ||
rs2004659 | 1 | 1.44E + 08 | NUDT17 | intron | – | A/G | A | G | 0.629111 | 0.2478 | 0.995249 | SNP_A_2211220 |
rs3806218 | 1 | 1.45E + 08 | BCL9 | near-g | + | C/T | C | T | 0.655718 | 0.1067 | 0.998812 | SNP_A_8575283 |
rs2352866 | 1 | 1.46E + 08 | + | C/T | T | C | 0.980535 | 1 | 0.998812 | SNP_A_8635861 | ||
rs4637157 | 2 | 19443 | + | C/T | T | C | 0.906326 | 1 | 1 | SNP_A_8500963 | ||
rs11903036 | 2 | 584324 | – | G/T | G | T | 0.53163 | 0.7181 | 1 | SNP_A_8639506 | ||
rs4549126 | 2 | 714368 | – | C/T | T | C | 0.614964 | 0.448 | 1 | SNP_A_8430739 | ||
rs6758300 | 2 | 75483393 | – | A/G | G | A | 0.568735 | 0.8567 | 1 | SNP_A_2284162 | ||
rs4667937 | 2 | 1.67E + 08 | – | A/T | A | T | 0.739659 | 1 | 1 | SNP_A_1851057 | ||
rs6785370 | 3 | 3933764 | + | A/G | A | G | 0.874696 | 0.4383 | 0.996437 | SNP_A_4202617 | ||
rs7628979 | 3 | 4321347 | SETMAR | intron | + | G/T | T | G | 0.529197 | 0.07716 | 1 | SNP_A_4290525 |
rs711664 | 3 | 4437544 | SUMF1 | intron | + | C/T | C | T | 0.706204 | 0.6558 | 1 | SNP_A_2098242 |
rs35489229 | 3 | 5088187 | – | A/G | A | G | 0.892336 | 1 | 1 | SNP_A_2299978 | ||
rs1524557 | 3 | 81974721 | – | A/G | A | G | 0.639903 | 0.4311 | 1 | SNP_A_2123904 | ||
rs1466475 | 4 | 80175727 | – | C/T | T | C | 0.81691 | 0.01551 | 1 | SNP_A_2063157 | ||
rs2615479 | 4 | 88797334 | DMP1 | intron | – | C/T | C | T | 0.71837 | 1 | 1 | SNP_A_1862590 |
rs6849123 | 4 | 91684534 | MGC48628 | intron | – | A/G | G | A | 0.894769 | 1 | 1 | SNP_A_8414444 |
rs4267808 | 4 | 1.1E + 08 | COL25A1 | intron | – | G/T | T | G | 0.871655 | 1 | 1 | SNP_A_2063127 |
rs9992755 | 4 | 1.11E + 08 | EGF | intron | + | A/G | A | G | 0.686131 | 0.5216 | 1 | SNP_A_1873873 |
rs11951861 | 5 | 84715767 | – | A/G | A | G | 0.827251 | 0.5626 | 1 | SNP_A_8538997 | ||
rs1428900 | 5 | 84909967 | – | C/T | C | T | 0.731144 | 0.2558 | 1 | SNP_A_2241509 | ||
rs17207011 | 5 | 85486010 | + | A/C | C | A | 0.886861 | 1 | 1 | SNP_A_8651237 | ||
rs372106 | 5 | 1.23E + 08 | + | A/G | G | A | 0.619221 | 0.8545 | 1 | SNP_A_1850833 | ||
rs7730187 | 5 | 1.68E + 08 | SLIT3 | intron | + | C/T | C | T | 0.518248 | 0.1095 | 1 | SNP_A_4282886 |
rs1482570 | 6 | 72738670 | RIMS1 | intron | – | C/G | C | G | 0.867397 | 0.4147 | 1 | SNP_A_2147869 |
rs1281958 | 6 | 1.53E + 08 | – | G/T | G | T | 0.587591 | 0.8568 | 1 | SNP_A_4222639 | ||
rs9479769 | 6 | 1.55E + 08 | OPRM1 | intron | – | A/C | A | C | 0.546837 | 0.5862 | 1 | SNP_A_2252195 |
rs9322560 | 6 | 1.56E + 08 | + | A/G | A | G | 0.857664 | 0.7365 | 1 | SNP_A_2204739 | ||
rs9457675 | 6 | 1.6E + 08 | – | G/T | G | T | 0.641728 | 0.8483 | 1 | SNP_A_2109851 | ||
rs4721428 | 7 | 2137132 | MAD1L1 | intron | + | A/G | A | G | 0.678832 | 0.03313 | 1 | SNP_A_8644552 |
rs6461984 | 7 | 3314009 | SDK1 | intron | + | A/G | A | G | 0.703771 | 1 | 0.997625 | SNP_A_8500870 |
rs17186478 | 7 | 5779274 | RNF216 | intron | – | A/C | C | A | 0.603406 | 0.8521 | 1 | SNP_A_2276119 |
rs2110333 | 7 | 8151614 | ICA1 | intron | + | C/T | T | C | 0.708029 | 0.09075 | 1 | SNP_A_8699267 |
rs1352090 | 7 | 46160368 | – | C/G | G | C | 0.615572 | 0.364 | 1 | SNP_A_8478994 | ||
rs4733163 | 8 | 33653826 | – | A/G | G | A | 0.625304 | 0.09864 | 1 | SNP_A_8357393 | ||
rs2981182 | 8 | 40010613 | – | A/C | C | A | 0.53528 | 0.03005 | 1 | SNP_A_8501882 | ||
rs2923408 | 8 | 42570683 | + | A/G | A | G | 0.542579 | 0.7232 | 1 | SNP_A_2264082 | ||
rs16921991 | 8 | 58386566 | + | C/T | T | C | 0.796837 | 0.2484 | 1 | SNP_A_4212967 | ||
rs10955119 | 8 | 98468181 | – | C/G | G | C | 0.58455 | 0.01847 | 1 | SNP_A_1873431 | ||
rs7036143 | 9 | 90615114 | – | C/T | T | C | 0.827859 | 1 | 1 | SNP_A_8332992 | ||
rs2196921 | 9 | 91748045 | – | C/T | C | T | 0.81691 | 0.4025 | 1 | SNP_A_8714258 | ||
rs12238738 | 9 | 95433628 | PHF2 | intron | – | C/T | T | C | 0.622263 | 0.02467 | 1 | SNP_A_2103415 |
rs10984103 | 9 | 99679096 | – | G/T | G | T | 0.652068 | 1 | 1 | SNP_A_8701456 | ||
rs1989773 | 9 | 1.17E + 08 | + | A/G | G | A | 0.990876 | 1 | 1 | SNP_A_8526939 | ||
rs10887185 | 10 | 85670555 | + | C/G | C | G | 0.914234 | 0.09797 | 1 | SNP_A_1799218 | ||
rs481179 | 10 | 1.08E + 08 | + | C/T | T | C | 0.576642 | 0.7135 | 1 | SNP_A_8706770 | ||
rs17586536 | 10 | 1.2E + 08 | C10orf46 | intron | + | C/T | T | C | 0.639903 | 1 | 1 | SNP_A_8582485 |
rs10788015 | 10 | 1.22E + 08 | – | C/T | T | C | 0.569343 | 0.7223 | 1 | SNP_A_8527983 | ||
rs4339955 | 10 | 1.22E + 08 | + | C/T | T | C | 0.78528 | 0.8055 | 1 | SNP_A_8334121 | ||
rs11030861 | 11 | 29853551 | – | A/G | G | A | 0.937956 | 1 | 1 | SNP_A_1788514 | ||
rs7947279 | 11 | 82018398 | + | C/T | T | C | 0.893552 | 0.1277 | 1 | SNP_A_8345915 | ||
rs10895219 | 11 | 1.01E + 08 | ANGPTL5 | intron | – | C/T | T | C | 0.965937 | 1 | 1 | SNP_A_8703545 |
rs9888281 | 11 | 1.26E + 08 | KIRREL3 | intron | – | G/T | T | G | 0.799878 | 0.5658 | 1 | SNP_A_2206833 |
rs10790956 | 11 | 1.28E + 08 | ETS1 | intron | – | C/T | C | T | 0.565085 | 1 | 1 | SNP_A_2253706 |
rs7138234 | 12 | 21569984 | C12orf39 | near-g | + | C/T | T | C | 0.994526 | 1 | 1 | SNP_A_4277693 |
rs12426560 | 12 | 41977227 | – | C/T | C | T | 0.814477 | 0.2236 | 1 | SNP_A_8404603 | ||
rs11183911 | 12 | 46055518 | + | A/G | A | G | 0.818735 | 0.7645 | 1 | SNP_A_1956756 | ||
rs11113259 | 12 | 1.06E + 08 | + | C/T | C | T | 0.999392 | 1 | 0.998812 | SNP_A_2030476 | ||
rs10219441 | 12 | 1.15E + 08 | – | C/T | T | C | 0.692214 | 0.5258 | 1 | SNP_A_4223101 | ||
rs4427687 | 13 | 73781335 | – | G/T | G | T | 0.757299 | 0.1453 | 0.998812 | SNP_A_2003390 | ||
rs9318328 | 13 | 74726372 | + | A/T | T | A | 0.541971 | 0.8591 | 0.998812 | SNP_A_1854478 | ||
rs9573791 | 13 | 75607873 | – | A/G | A | G | 0.902068 | 1 | 1 | SNP_A_2160026 | ||
rs2329072 | 13 | 77858815 | + | C/T | T | C | 0.594282 | 0.6994 | 1 | SNP_A_2162287 | ||
rs2633019 | 13 | 82465113 | – | A/G | A | G | 0.530414 | 1 | 1 | SNP_A_2024048 | ||
rs12897163 | 14 | 59385513 | RTN1 | intron | + | A/C | A | C | 0.751217 | 0.3606 | 1 | SNP_A_2233795 |
rs2121063 | 14 | 75798908 | + | C/G | G | C | 0.893552 | 0.2988 | 1 | SNP_A_4298064 | ||
rs1676295 | 14 | 76103995 | – | C/G | C | G | 0.789538 | 1 | 1 | SNP_A_2003847 | ||
rs1430569 | 14 | 86878849 | – | C/T | C | T | 0.53528 | 0.374 | 1 | SNP_A_2185553 | ||
rs6575695 | 14 | 98363450 | – | C/T | C | T | 0.973236 | 1 | 1 | SNP_A_2133926 | ||
rs1390876 | 15 | 45433081 | – | C/T | C | T | 0.595499 | 0.06189 | 1 | SNP_A_2277486 | ||
rs13313462 | 15 | 45534066 | – | C/T | T | C | 0.620438 | 0.8445 | 1 | SNP_A_8421063 | ||
rs7180426 | 15 | 60558330 | – | C/T | C | T | 0.859489 | 1 | 1 | SNP_A_8713038 | ||
rs17477813 | 15 | 76147746 | TBC1D2B | intron | – | C/T | T | C | 0.692214 | 0.831 | 1 | SNP_A_8395279 |
rs2072986 | 16 | 1631107 | CRAMP1L | intron | – | A/G | A | G | 0.847324 | 1 | 1 | SNP_A_8348939 |
rs1077836 | 16 | 10248642 | – | G/T | T | G | 0.66545 | 0.7045 | 1 | SNP_A_2287848 | ||
rs8052975 | 16 | 10856764 | + | C/T | C | T | 0.711679 | 1 | 1 | SNP_A_8486961 | ||
rs6497651 | 16 | 23040046 | USP31 | intron | + | C/T | C | T | 0.975669 | 1 | 1 | SNP_A_8525616 |
rs27817 | 16 | 48013792 | + | A/G | G | A | 0.97202 | 1 | 0.997625 | SNP_A_8365337 | ||
rs9897174 | 17 | 49611224 | + | G/T | G | T | 0.948905 | 1 | 1 | SNP_A_2309201 | ||
rs345168 | 17 | 55565566 | – | A/G | G | A | 0.959854 | 1 | 1 | SNP_A_1796579 | ||
rs9908999 | 17 | 56215981 | BCAS3 | intron | + | A/G | A | G | 0.909367 | 0.5936 | 1 | SNP_A_1848643 |
rs1112364 | 17 | 57597131 | + | C/T | C | T | 0.905718 | 0.4362 | 1 | SNP_A_8550334 | ||
rs12936559 | 17 | 57680004 | + | A/G | G | A | 0.935523 | 1 | 1 | SNP_A_8410067 | ||
rs1318841 | 18 | 17138521 | – | C/T | C | T | 0.967153 | 1 | 1 | SNP_A_2087816 | ||
rs17202807 | 18 | 19434594 | ANKRD29 | utr-3 | + | G/T | T | G | 0.955596 | 1 | 0.998812 | SNP_A_2132404 |
rs339869 | 18 | 20461587 | + | A/G | A | G | 0.55292 | 0.4779 | 1 | SNP_A_8437981 | ||
rs11083025 | 18 | 49698325 | – | A/G | G | A | 0.930657 | 1 | 1 | SNP_A_1888265 | ||
rs4325666 | 18 | 65460176 | DOK6 | intron | – | C/T | C | T | 0.933698 | 1 | 1 | SNP_A_1924329 |
rs8111862 | 19 | 12420713 | – | C/T | C | T | 0.51399 | 0.5942 | 1 | SNP_A_2179593 | ||
rs2453888 | 19 | 22423985 | – | C/G | G | C | 0.849757 | 0.03764 | 1 | SNP_A_8549134 | ||
rs16999009 | 19 | 22701498 | + | A/G | G | A | 0.877129 | 0.2534 | 1 | SNP_A_2094893 | ||
rs7252281 | 19 | 35965262 | + | G/T | T | G | 0.65204 | 0.1049 | 0.98337 | SNP_A_1867428 | ||
rs7254832 | 19 | 43637691 | RYR1 | intron | + | C/T | C | T | 0.871046 | 0.7148 | 1 | SNP_A_1791707 |
rs1974821 | 19 | 56609547 | LOC10012 | coding | – | C/T | C | T | 0.852798 | 1 | 1 | SNP_A_8587419 |
rs6056690 | 20 | 9475353 | PAK7 | intron | – | C/T | T | C | 0.850365 | 0.1277 | 1 | SNP_A_2250060 |
rs1415774 | 20 | 33229277 | PROCR | near-g | – | C/T | C | T | 0.566302 | 0.4777 | 1 | SNP_A_2130084 |
rs6093657 | 20 | 40549705 | PTPRT | intron | + | A/G | A | G | 0.877737 | 1 | 1 | SNP_A_8463206 |
rs7260668 | 20 | 42919440 | – | A/G | A | G | 0.694039 | 0.8358 | 1 | SNP_A_1875543 | ||
rs13042657 | 20 | 44356316 | – | C/T | C | T | 0.784063 | 0.7955 | 1 | SNP_A_8623899 |