Table 1 Summary of significant interactions, Variant annotations are from Ensembl [29]. Base model covariate selection is based on significance at the 0.05 level and includes average pre-treatment triglyceride level, age, center, current smoker status, and sex
SNP | Alleles | MAF | Location | Gene | Consequence type | LRT p-value |
|---|---|---|---|---|---|---|
rs1362571 | G/T | 0.34 (G) | 16:53877858 | FTO | Intron variant | 2.76 × 10− 6 |
rs11655588 | A/G | 0.18 (G) | 17:18204137 | ALKBH5 | Intron variant | |
rs10521304 | T/C | 0.41 (C) | 16:53874745 | FTO | Intron variant | 8.80 × 10− 6 |
rs11655588 | A/G | 0.18 (G) | 17:18204137 | ALKBH5 | Intron variant | |
rs1421090 | A/G | 0.29 (G) | 16:53816258 | FTO | Intron variant | 0.000158 |
rs8071834 | T/C | 0.45 (C) | 17:18196677 | ALKBH5 | Intron variant | |
rs17820875 | A/G | 0.12 (G) | 16:53892878 | FTO | Intron variant | 0.000177 |
rs8068517 | G/A | 0.24 (G) | 17:18192664 | ALKBH5 | Intron variant |