Skip to main content

Table 4 Performance across sets of SNP-CpG variant pairs containing major-effect variants

From: Evaluating the performance of gene-based tests of genetic association when testing for association between methylation and change in triglyceride levels at GAW20

Gene Total SNP heritability No. SNP-CpG pairs Sum lnp Sum-ln2p Minp pT 0.10 pT 0.05 pT 0.01 Single marker
CAUSAL5 0.375 5 1.00 1.00 1.00 1.00 1.00 1.00 1.00
UNION5 0.375 288 0.73 0.86 0.74 0.93 0.92 0.89 0.70
UNION2 0.125 92 0.23 0.26 0.26 0.25 0.26 0.27 0.23
NOISE5 0.375 288 0.06 0.11 0.64 0.50 0.61 0.70 0.64
NOISE2 0.125 92 0.03 0.09 0.20 0.14 0.15 0.18 0.20