Skip to main content

Table 2 Top 10 genes associated with natural logarithm change in triglycerides

From: Integrative methylation score to identify epigenetic modifications associated with lipid changes resulting from fenofibrate treatment in families

MMLT

SKATa

Genes

N

Effect size

SE

p Value

FDR q value

Genes

N

Q-statistic

p Value

FDR q value

CSHL1

3

1.29

0.35

2.02E-04

0.999

RPL29

1

117.39

1.59E-03

0.855

C22orf39

4

−1.89

0.56

7.74E-04

0.999

GJB5

2

104.51

2.95E-03

0.855

C14orf166

4

2.63

0.81

1.19E-03

0.999

TBX20

2

104.51

2.95E-03

0.855

RPL29

1

0.91

0.29

1.41E-03

0.999

WDR92

7

436.86

3.75E-03

0.855

PRPH

42

0.95

0.30

1.57E-03

0.999

CPT1A

6

439.50

3.92E-03

0.855

GSG1

2

−1.28

0.41

2.07E-03

0.999

MIR1266

2

51.56

5.29E-03

0.855

LPIN2

41

−0.95

0.32

2.55E-03

0.999

TIMP4

5

191.94

7.11E-03

0.855

IP6K3

124

−1.26

0.42

2.61E-03

0.999

ZNF788

5

191.94

7.11E-03

0.855

PPIC

53

−0.90

0.31

3.63E-03

0.999

GSG1

2

105.07

8.14E-03

0.855

RHBDL3

21

0.49

0.17

3.94E-03

0.999

CRYGA

3

115.23

1.06E-02

0.855

  1. FDR, false discovery rate; N, number of CpG sites in the gene set
  2. aThe weight of SKAT all equaled 1