Table 1 Type I error rates for both rare and common variants in the presence of main effects (top panel) and in the absence of main effects (bottom panel) for n = 2000
From: Methods to evaluate rare variants gene-age interaction for triglycerides
α-level | TOW-SE | iSKAT | VW-TOW-SE | |
|---|---|---|---|---|
With main effect | ||||
n = 2000 | 0.050 | 0.050 | 0.055 | 0.059 |
0.010 | 0.011 | 0.012 | 0.015 | |
0.001 | 0.000 | 0.001 | 0.000 | |
Without main effect | ||||
n = 2000 | 0.05 | 0.051 | 0.061 | 0.056 |
0.01 | 0.011 | 0.013 | 0.009 | |
0.001 | 0.000 | 0.003 | 0.001 | |