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Table 3 Region size effect analysis for the three methods based on the region of rs4399565

From: Methods to evaluate rare variants gene-age interaction for triglycerides

Region size

Median of MAF (range)

P TOW-SE

P iSKAT

P VW-TOW-SE

10 SNPs

0.006 (0.001–0.449)

0.022

0.023

0.019

20 SNPs

0.008 (0.001–0.449)

0.014

0.018

0.015

30 SNPs

0.008 (0.001–0.449)

0.013

0.014

0.012