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Fig. 2 | BMC Proceedings

Fig. 2

From: Homozygosity disequilibrium associated with treatment response and its methylation regulation

Fig. 2

Genome-wide homozygosity association analysis and meQTL analysis, with concomitant adjustment for sex, age, field center, smoking status, IDF, and 10 principal components. a, The results of genome-wide homozygosity association tests for TG response to fenofibrate are shown in a Manhattan plot. The vertical axis represents the p values (−log10 scale) of the homozygosity association tests. The horizontal axis represents the physical positions of the anchor SNPs of sliding windows by chromosome. b, The results of meQTL analyses for the fenofibrate-associated HD on MACROD2 in chromosome 20p12. The vertical axis represents the p values (−log10 scale) of the association tests. The horizontal axis represents the physical positions of the CpG sites by chromosome

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