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Table 1 Simulated data: association of 10 candidate CpG markers and their ROIs with post-lnTG adjusted for pre-lnTG and age

From: Relating drug response to epigenetic and genetic markers using a region-based kernel score test

ROI

CpG ID

KST, Window Size

Regression

±15 kbp

±3 kbp

±0 kbp

ROI-1

cg00000363

0.86

0.15

0.37

0.49

ROI-2

cg10480950

0.09

0.09

0.58

0.63

ROI-3

cg18772399

0.65

0.65

0.56

0.57

ROI-4

cg00045910

0.61

0.71

0.73

0.89

ROI-5

cg01242676

0.49

0.33

0.49

0.57

ROI-6

cg00703276

0.13

0.13

0.53

0.62

ROI-7

cg01971676

0.51

0.51

0.97

0.98

ROI-8

cg11736230

0.79

0.83

0.22

0.18

ROI-9

cg12598270

0.15

0.15

0.69

0.81

ROI-10

cg00001261

0.78

0.79

0.58

0.61

  1. p Values were computed by KST with varying window sizes including the CpG marker or by single-marker linear regression
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BMC Proceedings

ISSN: 1753-6561

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