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Table 1 Summary of country situation update as reported by country representatives

From: Cholera prevention and control in Asian countries

Thematic/Country

Bangladesh

Cambodia

India

Indonesia

Epidemiology

Endemic, and seasonal outbreaks

CFR 25 to 50% without treatment and 1% with treatment

Not cholera endemic, sporadic cases in 18 provinces.

CFR <1% but higher in hard to reach villages

Endemic with an estimated 834,00 cholera cases and 25,000 deaths every year

Several states do not report any cholera cases potentially due to limited surveillance system

Low endemic. No outbreaks since 2011

Incidence of diarrheal diseases for all age population is 350/1000 population and 670/ 1000 children < 5 years old

WASH

Lack of water pipe

Data not available

Open defecation with limited availability of safe drinking water supply mainly in rural area

Sharing sanitation facilities with other households

Practice of healthy and hygienic behavior by only 38.7%

Open defecation practiced by 9.4% population (2.5 millions), 10.9% use unsafe water, 7.3% drinks uncooked water

OCV vaccination

OCV included in national plan for at risk groups.

Technology transfer for vaccine development in country

Locally produced Vaccine (Cholvax) will be implemented

None

Vaccine introduction study done in Odisha state

OCV vaccine is not part of the EPI program

None

Surveillance/Diagnostic

Hospital based surveillance at 2% Nationwide surveillance on- going at 21 sites

Event based surveillance, laboratory confirmed (CamEWARN)

Surveillance of Acute Watery Diarrhea through CAM EWARN

Reporting of laboratory confirmed cholera cases to CDC Dept

Outbreak investigations

Weekly surveillance system in all regions

Guidelines and SOP for early case detection

Global positioning system & Google Earth in the investigation cholera outbreak.

Continuous laboratory surveillance of ADD in all districts

Visit of collector to affected sites for monitoring quick action

 

Advocacy

Advocacy meeting: January 2017

Communications (TV and radio spots, posters, flyers)

Community mobilization

Sensitization of PRI members, local PHC staff, ASHA, AWW and community

Other modes of community mobilization such as interpersonal Communication by door-to-door visit

 

Challenges

Licensure and funding for locally produced vaccine (Cholvax) deployment, with WHO pre-qualification

Inadequate coverage of the surveillance system

Under-reporting of surveillance systems

Marginalized rural and tribal populations

Poor availability of safe drinking water supply

Inadequate ownership of programs

Poor local health infrastructure

Inadequate priority setting mechanisms

Long incubation periods for research programs

Introduction of OCV

Under-reporting

Lack of RDT

Thematic/Country

Malaysia

Nepal

Pakistan

Epidemiology

Not Endemic except in Sabah region

Incidence rate <1 per 100,000 populations and CFR <1% in recent years

Malaysian: Foreigners incidence rate = 80:20.

Cycle pick every 3 years

Endemic, frequent outbreaks mainly during rainy season

5042 ADD cases and 169 laboratory confirmed Cholera cases reported mainly from Kathmandu valley (150/169). No deaths occurred.

Endemic

4-6 episodes of diarrhea per child per year < 5 year

Under five deaths per year from Diarrhea: 13.2%

WASH

Scarce safe water supply in some areas

Unresolved environmental issues – excreta, solid waste

Poor hygiene & food sanitation with cross border crossing and illegal coastal and urban settlements

Suboptimal WASH status

Basic Water Supply coverage: 83.59%, Sanitation: 87.17%. Hand-washing: 72.5%

16M do not have access to clean drinking water

27% consume tap water, 86% have access to improved water source, 73% have access to sanitation facilities

13% no toilet facility

OCV vaccination

Vaccine and antimicrobial prophylaxis

OCV not in EPI but available in the private health facilities

Oral prophylaxis for close contacts and food handlers

Reactive OCV Vaccination in Rautahat district in 2014.

Preventive OCV vaccination campaign in Nuwakot and Dhading in 2015 and in Banke district in 2016

OCV not registered

Surveillance/diagnostic

Mandatory web based within 24-hour notification

National guidelines and laboratory diagnostic capacity in all laboratories

Regulatory Infrastructure

Cholera is an EWARS reportable disease.

Clinical cases reported monthly from health facilities through existing HMIS system.

Cholera Surveillance embedded in the existing AMR sentinel surveillance system using 18 sites.

Comprehensive Targeted Interventions (CTI) to Control Cholera in Kathmandu Valley in Kathmandu valley in 2016

Facility based surveillance system in place in the province of Punjab since 2011(which has 60% of the population of Pakistan

limited laboratory capacity

Passive case- based surveillance from large hospitals of major cities, and WHO EMRO Documents and reports of NGOs working in disaster situations

Advocacy

Political commitment, interagency collaboration and coordination

Legal approach for child education, case notification and management, food sanitation

Subsidy for the poor (rural and urban)

Ensure accessibility to affordable healthcare and education

Free treatment and quarantine leave for working parents

Restructure settlements with affordable homes

Hygiene Promotion, community engagement, Social Mobilization campaign adapted to local culture

Door to Door Awareness Campaign.

Community Level Intervention: Booth Campaigns – Strategic Locations

-Awareness rallies

-Miking (In mobile vehicle and also during rallies)

-Awareness sessions to community groups and key community actors

-Food and food outlet inspection- Food authority and Municipality

-Mass communication by various media and special programs

-Schools reached to educate and use children on Cholera and prevention

 

Challenges

Cross border crossing

Illegal coastal and urban poor settlements

Poverty, illiteracy and language barrier

Inadequate financial investment for WASH

Identify risk groups and target mass vaccination by strengthening surveillance.

Need to give high priority to improve WASH status.

Enhance collaboration and coordination.

Advocacy needed to introduce the OCV vaccination

Endorse Cholera Prevention and Response National Road Map

Recurrent humanitarian emergencies

Weak surveillance system and underreporting

Limited laboratory capacity

Under resources of the public health control activities

Poor water and sanitation condition in conflict affected countries

Lack of cross border collaboration between the neighboring countries

Thematic/Country

Philippines

Thailand

Vietnam

Epidemiology

14,592 diarrheal and 96 deaths cases in 2016

124 (0.85%) were laboratory confirmed cholera

No deaths.

Incidence significantly decreased in the past decades while outbreaks occasionally occurred: 4 outbreaks since 2017

125 cases in 2015

Main transmitters: Employees of the seafood industry, Migrant population

No cholera outbreaks post-flood disasters in recent years

No Cholera since 2012

WASH

Zero Open Defecation Program.

Environmental Health Program: WASH, Regional Sanitary Engineers, Local Sanitary Inspectors

100% toilets at all houses

Sewage management

Chlorinated tap water and/or bottle water

Health education

Clean water supplies and Environment sanitation

Food hygiene and safety

OCV vaccination

 

OCV in a special setting, population in the temporary shelter at Thai-Myanmar Border

Local vaccine production

NRA approved by QWHO;

Vaccination deployed in 16 provinces with high incidence and for high risk areas and populations

Surveillance/diagnostic

Event-based Surveillance

Epidemiology Bureau of the DOH, Program Manager

Regional Epidemiology & Surveillance Units

Regional Program Coordinators

Collection of human (rectal swab, stool) and environmental (water) samples.

Laboratory testing of water samples thru the use of Colilert machine.

Records review and active case finding

Random inspection of water refilling stations

Continuous surveillance of diarrhea cases

Food & Water-borne Program.

Regional Sanitary Engineers

Local Sanitary Inspectors

Hospital-based surveillance system

– Early detection of suspected cholera cases

– Laboratory confirmation

• Timely and proper management of patients

• Prompt investigation and control by the trained

Surveillance and rapid response teams (SRRTs).

Improving Sanitation and Chlorination of Water Supply

12 Regional Laboratory Centers of department of Medical Sciences.

Water and Food samples with 1% APW

National guidelines for cholera diagnosis, treatment, surveillance, response, control and prevention

Testing in dog slaughter houses and restaurants

Mobile teams for early detection and investigation of outbreaks

Urgent reporting to higher level of health care system

Close collaboration between treatment and preventive systems in reporting, specimen collection, and sharing specimen

Laboratory testing at national and regional Level

At district level: Specimen collection, storage and transportation; Microscope examination, Gram staining,

Testing of water, fresh vegetables in restaurants and markets

Advocacy

The Department of Health (DOH) recognized the distinctive link between sanitation and better health, need for a new vision in sanitation, expressed in clearer policy and action programs

 

Enhance the leadership of political system and of Local Steering Committee on cholera prevention and control Mobilize whole political system in cholera prevention and control.

Close collaboration between related sectors on food hygiene and safety, clean water supply and environmental sanitation, education, information, transportation

Challenges

 

Continuing improvement of sanitation and safe water

Limited vaccination.

Varying capacity in diagnosis and treatment.

Maintaining and improving the clean water supply and environment sanitation program.

Strengthen collaboration among neighboring countries on sharing information and cholera control