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Table 3 The eradication biofilm formation of 1-monolaurin or rifampicin on S. epidermidis clinical isolates

From: The 1-monolaurin inhibit growth and eradicate the biofilm formed by clinical isolates of Staphylococcus epidermidis

S. epidermidis clinical isolate

TSB Media

Compound

Concentration (μg/mL)

OD ± SD

BEC

(%)

BEC50

(μg/mL)

BEC80

(μg/mL)

+

+

O

0.463

±

0.041

0

O

+

O

0.106

±

0.006

100

+

+

DMSO 5%

0.476

±

0.090

−3.641

+

+

1-monolaurin

1000

0.165

±

0.018

83.380

322.504

1338.681

500

0.219

±

0.039

68.161

250

0.363

±

0.064

27.918

125

0.398

±

0.033

18.114

62.5

0.372

±

0.070

25.397

31.25

0.423

±

0.082

11.111

15.625

0.433

±

0.064

8.403

7.813

0.465

±

0.077

−0.654

3.906

0.465

±

0.038

−0.654

1.953

0.392

±

0.082

19.701

+

+

Rifampicin

250

0.118

±

0.010

96.452

5.547

17.910

125

0.114

±

0.011

97.666

62.5

0.107

±

0.002

99.720

31.25

0.123

±

0.011

95.238

15.625

0.204

±

0.016

77.362

7.813

0.221

±

0.052

67.787

3.906

0.278

±

0.060

51.727

1.953

0.394

±

0.100

19.328

0.977

0.450

±

0.105

3.548

0.488

0.466

±

0.121

2.708