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Table 1 (abstract P-326). Productivity assessment of CHL-YN cells vs. CHO-K1 cells. Expression of the two IgG1 types was validated in flask-batch cultures of transfected hetero cell pools

From: Abstracts from the 26th European Society for Animal Cell Technology Meeting - Cell culture technologies: bridging academia and industry to provide solutions for patients

Antibody

Medium

Cell

Specific growth rate (h-1)

Doubling time (h)

Specific production rate (pg cell-1 h-1)

MAB1 (IgG1)

EX-CELL CD

CHO-K1

0.035

19.8

0.51

CHL-YN

0.062

11.1

0.86

JX G017-MAB01

CHO-K1

0.035

19.7

0.73

CHL-YN

0.065

10.7

1.18

MAB2 (IgG1)

EX-CELL CD

CHO-K1

0.034

20.1

0.68

CHL-YN

0.056

12.3

0.28

JX G017-MAB01

CHO-K1

0.034

20.6

0.71

CHL-YN

0.050

13.9

0.46