Table 1 (abstract A5). Study characteristics

Ostojic et al. [1]

48

RCT

GAA (1.2 ^a, 2.4 ^b, or 4.8 ^c gr/d) or placebo ^d for 6 weeks

Handgrip strength ↑ ^{a, b, c}

1 RM Bench press ↑ ^{a, b, c}

Vertical jump ↔ ^{a, b, c, d}

Anaerobic power ↔ ^{a, b, c, d}

Aerobic capacity ↔ ^{a, b, c, d}

Semeredi et al. [2]

14

RCCT

1 gr of GAA and 3 gr of creatine/d ^a or

4 gr/d of creatine for 4 weeks ^b

Total creatine ↑ ^{a, b}

Brain creatine ↑ ^{a, b}

1RM Bench press ↑ ^{a, b}

tHcy (μmol/L) ↔ ^a

VO2max ↔ ^{a, b}

Ostojic et al. [3]

24

RCT

GAA (2.4 gr/d) ^a or placebo ^b by oral administration for 6 weeks

Serum GAA ↑ ^a

Serum creatine ↑ ^a

Serum creatinine ↑ ^a

Serum tHcy ↑ ^a

Serum AST↔ ^{a, b}

Ostojic et al. [4]

24

RCT

2·4 gr GAA/d ^a, or 2·4 gr/d of GAA with 1·6 gr/d of betaine hydrochloride, 5 mg/d of vitamin B12, 10 mg/d of vitamin B6, and 600 mg/d of folic acid ^b

Serum creatine ↑ ^{a, b}

Serum tHcy ↑ ^a, ↔ ^b

Ostojic et al. [5]

48

RCT

GAA (1.2 ^a, 2.4 ^b, or 4.8 ^c gr/d) or placebo (Inulin) ^d for 6 weeks

Serum GAA ↑ ^{a, b, c}

Serum creatine ↑ ^{a, b, c}

Serum creatinine ↑ ^{a, b, c}

Vitamin B6, B12 ↔ ^{a, b, c, d}

tHcy (μmol/L) ↔ ^{a, b, d}; ↑ ^c

Ostojic et al. [6]

n=10

UINT

2 gr of GAA and 2 gr of creatine/d for 4 weeks

tHcy (μmol/L) ↑