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Volume 1 Supplement 1

Genetic Analysis Workshop 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci

Proceedings

Genetic Analysis Workshop 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci. Go to conference site.

St. Pete Beach, Florida, USA11-15 November 2006

Page 4 of 4

  1. The goal of this paper is to investigate the effects of normalization procedures for expression data on linkage results. We selected the two most commonly used expression data extraction and normalization meth...

    Authors: Mariza de Andrade, Elizabeth J Atkinson, Brooke L Fridley, Ellen L Goode, Shannon McDonnell, Wen Liu-Mares, Kari G Rabe, Zhifu Sun and Susan L Slager

    Citation: BMC Proceedings 2007 1(Suppl 1):S151

    Content type: Proceedings

    Published on:

  2. "Genetical genomics", the study of natural genetic variation combining data from genetic marker-based studies with gene expression analyses, has exploded with the recent development of advanced microarray tech...

    Authors: Yoonhee Kim, Betty Q Doan, Priya Duggal and Joan E Bailey-Wilson

    Citation: BMC Proceedings 2007 1(Suppl 1):S152

    Content type: Proceedings

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  3. We evaluate the impact of three pre-processing methods for Affymetrix microarray data on expression quantitative trait locus (eQTL) mapping, using 14 CEPH Utah families (GAW Problem 1 data). Different sets of ...

    Authors: Aurelie Labbe, Marie-Paule Roth, Pierre-Hugues Carmichael and Maria Martinez

    Citation: BMC Proceedings 2007 1(Suppl 1):S153

    Content type: Proceedings

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  4. To explore the mapping of factors regulating gene expression, we have carried out linkage studies using expression data from individual transcripts (from Affymetrix microarrays; Genetic Analysis Workshop 15 Pr...

    Authors: Jeanette N McClintick, Yunlong Liu and Howard J Edenberg

    Citation: BMC Proceedings 2007 1(Suppl 1):S155

    Content type: Proceedings

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  5. Variance-components and regression-based methods are frequently used to map quantitative trait loci. The normality of the trait values is usually assumed and violation of this assumption can have a detrimental...

    Authors: Bo Peng, Robert K Yu, Kevin L DeHoff and Christopher I Amos

    Citation: BMC Proceedings 2007 1(Suppl 1):S156

    Content type: Proceedings

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  6. Recent studies have shown that linkage disequilibrium (LD) between single-nucleotide polymorphism (SNP) markers is widespread. Assuming linkage equilibrium has been shown to cause false positives in linkage st...

    Authors: Cornelis A Albers and Hilbert J Kappen

    Citation: BMC Proceedings 2007 1(Suppl 1):S159

    Content type: Proceedings

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  7. We performed a multipoint linkage analysis for rheumatoid arthritis (RA) using high-density single-nucleotide polymorphism (SNP) data for chromosome 6 and chromosome 21 using Genetic Analysis Workshop 15 (GAW1...

    Authors: Kristina Allen-Brady, Benjamin D Horne, Alka Malhotra, Craig Teerlink, Nicola J Camp and Alun Thomas

    Citation: BMC Proceedings 2007 1(Suppl 1):S160

    Content type: Proceedings

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  8. While high-throughput genotyping technologies are becoming readily available, the merit of using these technologies to perform genome-wide association studies has not been established. One major concern is tha...

    Authors: Hua Tang, Jie Peng, Pei Wang, Marc Coram and Li Hsu

    Citation: BMC Proceedings 2007 1(Suppl 1):S162

    Content type: Proceedings

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  9. A number of autoimmune and other diseases have well established HLA associations; in many cases there is strong evidence for the direct involvement of the HLA class II peptide-presenting antigens, e.g., HLA DR...

    Authors: Glenys Thomson and Ana Maria Valdes

    Citation: BMC Proceedings 2007 1(Suppl 1):S163

    Content type: Proceedings

    Published on:

  10. In whole-genome association studies, at the first stage, all markers are tested for association and their test statistics or p-values are ranked. At the second stage, some most significant markers are further ana...

    Authors: Gang Zheng, Jungnam Joo, Jing-Ping Lin, Mario Stylianou, Myron A Waclawiw and Nancy L Geller

    Citation: BMC Proceedings 2007 1(Suppl 1):S165

    Content type: Proceedings

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  11. We studied the impact of marker density on the accuracy of association mapping using Genetic Analysis Workshop 15 simulated dense single-nucleotide polymorphism (SNP) data on chromosome 6. A total of 1500 case...

    Authors: Weihua Zhang, Winston Lau, Cheng Hu and Tai-Yue Kuo

    Citation: BMC Proceedings 2007 1(Suppl 1):S166

    Content type: Proceedings

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